What are the similarities and differences between feline and canine pancreatitis?

Feline and canine pancreatitis share many clinical features, but differ in presentation, diagnosis, and management. Cats often show subtler signs, while dogs tend to present more acutely.

Here’s a breakdown of the key similarities and differences between pancreatitis in cats and dogs:

🟢 Similarities

  • Pathophysiology: In both species, pancreatitis involves inflammation of the pancreas, often due to autodigestion from prematurely activated pancreatic enzymes Merck Veterinary Manual.
  • Risk of complications: Chronic pancreatitis in both cats and dogs can lead to exocrine pancreatic insufficiency and diabetes mellitus Veterinary Medical Association of New York City.
  • Diagnostic approach:
    • Blood tests (e.g., serum lipase levels)
    • Imaging (ultrasound)
    • Clinical signs and history
  • Treatment principles:
    • Supportive care: fluid therapy, pain management, antiemetics
    • Nutritional support: early feeding is encouraged once vomiting subsides
    • Management of underlying conditions

🔴 Differences

FeatureDogsCats
Common presentationAcute, often severeOften chronic or subclinical
Clinical signsVomiting, abdominal pain, lethargy, feverLethargy, anorexia, weight loss; vomiting is less common Merck Veterinary Manual
EtiologyOften idiopathic; linked to high-fat diets, obesity, certain drugsOften idiopathic; may be associated with hepatic lipidosis or inflammatory bowel disease Merck Veterinary Manual
Diagnosis challengesEasier to detect due to overt symptomsOften missed due to vague signs and overlapping conditions
Treatment optionsFuzapladib sodium approved for acute cases Merck Veterinary ManualNo specific feline-approved drugs; supportive care is primary

🧠 Clinical Insight

  • Cats often suffer from triaditis—a combination of pancreatitis, inflammatory bowel disease, and cholangitis—making diagnosis and treatment more complex.
  • Dogs may experience more dramatic episodes, but tend to respond more predictably to treatment.

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Sources: Veterinary Ireland Journal Veterinary Medical Association of New York City Merck Veterinary Manual