What is the connection between feline coronavirus and feline infectious peritonitis?

Feline coronavirus (FCoV) and feline infectious peritonitis (FIP) are closely related, but they represent different stages of a viral infection in cats:

🦠 Feline Coronavirus (FCoV)

  • A common and usually mild virus found in domestic cats.
  • Primarily affects the gastrointestinal tract, often causing no symptoms or only mild diarrhea.
  • Highly contagious, especially in environments with many cats (e.g., shelters, catteries).

🔄 Mutation to FIP

  • In a small percentage of infected cats, FCoV mutates into a more dangerous form.
  • This mutated virus gains the ability to infect white blood cells, allowing it to spread throughout the body.
  • This leads to feline infectious peritonitis (FIP), a severe and often fatal disease.

🧬 Feline Infectious Peritonitis (FIP)

  • Caused by the mutated form of FCoV.
  • Triggers a systemic inflammatory response, often affecting the abdomen, chest, eyes, or brain.
  • Comes in two forms:
  • Wet (effusive): fluid accumulation in body cavities.
  • Dry (non-effusive): granulomas form in organs, leading to varied symptoms.
  • FIP is not considered contagious like FCoV, as the mutation occurs within the individual cat.

In short, while many cats may carry FCoV without issue, FIP is a rare and serious consequence of a mutation in that virus.

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