Canine adenovirus type 2 (CAV-2) is caused by a virus that is transmitted through contact with respiratory secretions from infected dogs, such as coughing and sneezing². The virus can also be transmitted through contact with contaminated objects, such as food and water bowls, toys, and bedding². The incubation period for CAV-2 is typically 4-6 days¹.
CAV-2 is considered a core vaccine for dogs, primarily because it is necessary for the prevention of canine adenovirus type 1 (CAV-1), the cause of infectious canine hepatitis, historically recognized as a severe and often fatal disease of canids¹. Although uncommon, sporadic cases of CAV-1 infection are still reported¹. CAV-2 can also cause tracheobronchitis and is part of the canine infectious respiratory disease (CIRD) complex¹. Vaccination schedules for parenteral CAV-2 vaccines follow the recommendations for CDV and CPV, and CAV-2 is usually a component of combination vaccines¹. Given in combination with canine parainfluenza virus (CPIV) and Bordetella vaccines, MLV CAV-2 vaccine can be administered intranasally (IN) to puppies as young as 3 weeks of age, as mucosal immunity is not blocked by maternal derived antibodies¹.
In summary, CAV-2 is caused by a virus that is transmitted through contact with respiratory secretions from infected dogs, such as coughing and sneezing. It can also be transmitted through contact with contaminated objects, such as food and water bowls, toys, and bedding. CAV-2 is considered a core vaccine for dogs, primarily because it is necessary for the prevention of canine adenovirus type 1 (CAV-1), the cause of infectious canine hepatitis, historically recognized as a severe and often fatal disease of canids. Vaccination schedules for parenteral CAV-2 vaccines follow the recommendations for CDV and CPV, and CAV-2 is usually a component of combination vaccines¹.
Source:
(1) Adenovirus in Dogs: What You Need to Know — Pumpkin®. https://www.pumpkin.care/blog/adenovirus-in-dogs/.
(2) Canine Adenovirus (CAV) – AAHA. https://www.aaha.org/aaha-guidelines/2022-aaha-canine-vaccination-guidelines/key-vaccination-considerations-by-antigen/canine-adenovirus-cav/.
(3) Genetic Characteristics of Canine Adenovirus Type 2 Detected in Wild …. https://mdpi-res.com/d_attachment/vetsci/vetsci-09-00591/article_deploy/vetsci-09-00591-v2.pdf?version=1667293861.
(4) Frontiers | Novel Genotype Definition and the First Epidemiological …. https://www.frontiersin.org/articles/10.3389/fvets.2020.00534/full.
(5) Canine Adenovirus Type 2 | Merck Animal Health USA. https://www.merck-animal-health-usa.com/condition/canine-adenovirus-type-2.