The symptoms of canine distemper vary depending on the infection stage, virus virulence, and the dog’s immunity, mainly affecting the respiratory, digestive, and nervous systems. Specific manifestations are as follows:
Initial stage (3-6 days after infection): Similar to a cold, with a fever of 39.5-41°C (biphasic fever, i.e., fever for 1-2 days followed by a brief drop, then rising again), accompanied by listlessness, loss of appetite, and serous discharge from the eyes and nose.
Middle stage: Symptoms worsen and diversify.
Respiratory type: Coughing, sneezing, purulent nasal discharge and eye discharge, rales in the lungs, and easy secondary pneumonia.
Digestive type: Vomiting, diarrhea (stool with blood or mucus), and severe cases may lead to dehydration and electrolyte imbalance.
Skin type: A few dogs develop thickened footpads (“hard footpad disease”) or skin papules on the abdomen and groin.
Late stage (usually 2-4 weeks after infection): The virus invades the nervous system, causing irreversible symptoms such as local muscle twitching (corners of the mouth, limbs), epilepsy, circling, ataxia, limb rigidity, and coma, with an extremely high mortality rate.
Puppies and unvaccinated dogs have more severe symptoms and often die from multisystem failure; some recovered dogs may have residual neurological sequelae (such as lifelong convulsions).
Ringbio’s Canine Distemper Virus IgG Antibody ELISA Kit is used to detect CDV specific antibodies in canine serum and plasma, moreover, it can be used in the supervision of vaccine antibody levels in dogs. This kit is ready to be used for lab staff, and there is no special instruments are required during the operation, simply and accurately.
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