Most cats infected with Toxoplasma gondii show no symptoms at all, but when illness does occur, the most common signs are fever, loss of appetite, and lethargy . More severe symptoms depend on which organs are affected and are more likely in kittens or cats with weakened immune systems (e.g., FeLV or FIV).
๐พ Key symptoms of toxoplasmosis in cats
- Fever โ often one of the earliest signs.
- Loss of appetite โ may lead to weight loss.
- Lethargy โ reduced activity or weakness.
- Respiratory problems โ pneumonia can develop, causing worsening breathing difficulty .
- Jaundice โ yellowing of skin or gums if the liver is affected.
- Neurological signs โ seizures, circling, head pressing, difficulty swallowing, personality changes, or loss of coordination .
- Eye inflammation โ uveitis, abnormal pupils, blindness, or retinal inflammation .
- Muscle pain โ muscle hyperesthesia (pain when touched) is reported in some cases .
- Diarrhea โ usually mild and short-lived; occurs in a minority of infected cats .
๐ฑ How common is illness?
Most infected cats never show symptoms. Clinical toxoplasmosis is rare and usually appears when the immune system cannot control the parasite (e.g., kittens, FeLV/FIV-positive cats) .
๐งช When to worry
If a cat shows fever + lethargy + appetite loss, especially combined with breathing issues, jaundice, or neurological signs, a vet should evaluate them immediately. Diagnosis typically involves IgG/IgM antibody testing and sometimes imaging or tissue sampling.

